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Writing with Electrospinning

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SINERGIA: biofabrication for 3D in vitro models

We are excited to have been selected for funding in a Marie Curie project called SINERGIA, which aims at developing advanced models of human physiology and diseases, to be ultimately introduced in the preclinical stages of the drug discovery pipeline.

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Moroni Lab Broadcasted on Biofabrication

Biofabrication has witnessed several advances in this past months, spanning from new technologies, to promising steps forward in several tissue regeneration applications.

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Mimicking Tissue Organization at Multiple Scales with Biofabrication

Many tissues in our body display a variable degree of fiber curliness, which is crucial for their biomechanical behaviour. Methods to replicate such features in scaffolds for regenerative medicine are limited. Here, we show how by simply applying controlled buckling to electrospun fibers, we can fabricate scaffolds with different degrees of fiber waviness at multiple scales.

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Towards Kidney bioprinting

Certainly bioprinting of a full kidney remains a dream. It will be probably like that for many decades, unless a strong and well funded collaborative effort will be originated in the near future. However, current kidney bioprinting attempts are helping creating more know-how over kidney biology through the biofabrication of 3D in vitro models that can be used to study new treatments for kidney chronic conditions.

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World TERMIS 2021

After Seoul, Vienna, and Boston, Maastricht was selected to host the next world conference of the tissue engineering and regenerative medicine society. We expect to attract more than 2'000 delegates by 2021 in Maastricht, which is at the center of a European region fervidly active in tissue engineering, regenerative medicine, stem cells, biomaterials, in silico modeling, and biofabrication.

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Writing with Electrospinning
Published on: November 26, 2017
Category: Events

We have recently published our latest efforts in furhter expanding the biofabrication technology envelop, by introducing to the field a new electrospinning technology.Direct writing electrospinning adds to the current state of the art comprising melt electrospinning and near field electrospinning, by further controlling and focusing the applied electric field during processing. In this manner, we can create scaffolds comprised of bundles of microfibers that are deposited in a prescribed pattern. A proof of concet study showed the successful creation of scaffolds that can mimic the deposition of collagen tyep II fibers in articular cartilage:

http://pubs.acs.org/doi/10.1021/acsami.7b07151