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World TERMIS 2021

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Integrating Biofabrication Technologies

Unlocking the secrets of osteochondral regeneration has long been a daunting challenge, with the intricate interplay between cartilage and bone presenting formidable hurdles. However, a groundbreaking approach is on the horizon, poised to redefine the landscape of tissue regeneration: multiphasic scaffolds – the cornerstone of cutting-edge strategies aimed at mirroring the complexities of the osteochondral unit and nurturing the growth of implanted bone-marrow derived stem cells (BMSCs). Yet, amidst the promise, hurdles remain. Stem cell loss during expansion in vitro and the limited control over their behavior within scaffolds both in vitro and in vivo pose formidable challenges.

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Bioprinting in Space

In a new Pathfinder Open project, PULSE, we have partnered with different experts in space technology and use thereof to study how the Space environment could be working as an accelerator of ageing…

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New Hybrid Biofabrication technology

Many tissues in our body display gradients. These are not only biological gradients, but also structural, physical, and chemical ones, resulting in smoother variations of mechanical properties and cell functional activity.

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Kidney 3D in vitro models through bioprinting

At the Complex Tissue Regeneration department, we work hard to bridge the gap towards the dream of organs bioprinting. Step by step, we are now progressing towards understanding more and more in depth the requirements to bioprint different kidney cells, either derived from pluripotent stem cells or of adult species.

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Bioprinting through Levitation

Magnetic levitation offers the possibility to place cells in a precise position in space through controlling the magnetic forces applied to magnetized cells. This new biofabrication technique, at the interface between bioprinting and bioassembly, provides new ways to create large-scale biological constructs that can be used for regenerative medicine purposes.

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World TERMIS 2021
Published on: October 10, 2018
Category: Events

Maastricht is located in the heart of northern Europe, forming with Flanders and North Rhine Westphalia one of the most prolific and fermenting European region in tissue engineering and regenerative medicine. In Maastricht, the creation of the MERLN institute for Technology-Inspired Regenerative Medicine in 2015 brought new possibilities in the south of the Netherlands region, acting as a linking thread between the industrial Brightlands Chemelot Campus and the academic hospital in Maastricht. The creation of this ecosystem resulted in spurring of several regenerative medicine programs aiming at bringing to the clinics innovative treatments for skeletal, vascular, neural, and organ regeneration. The most ambitious of these programs is certainly the creation of RegMedXB, a public private partnership that connects Maastricht with other active centers in the Netherlands (Utrecht, Eindhoven) and Flanders (Leuven). A first example of this crossborder collaboration within the EU region is the Aachen-
Maastricht Institute for Biobased Materials, which brings together RWTH and Fraunhofer in Aachen with Maastricht University to work on new routes in biotechnology exploiting natural biologically derived materials.

The region Liège-Leuven-Maastricht-Eindhoven-Aachen punches above its weight in excellent regenerative medicine science. Expertise spans across all the disciplines represented in tissue engineering and regenerative medicine, from cell biology, medicine and clinical research to materials science, biofabrication and nano technologies. With university medical centers, science parks and financing opportunities, the region has solid infrastructure for translating science into practice, hosting an emerging regenerative medicine industry. The ambition of our European Region is to become an internationally leading virtual research institute in regenerative medicine that bundles the forces of the strong institutes in the region. Researchers and entrepreneurs will work side by side to perform and valorize the research defined around several solutions for large unmet medical needs. The institute will closely collaborate with companies, build strong patent positions and out-license them, and create new companies. Witnessing the centrality in European science and policy, Maastricht was also the hosting city for the Treaty on European Union, signed in 1992.

The conference is organized together with Prof. Geris (University of Liege and Catholic University of Leuven) and Prof. Jockenhoevel (Maastricht University and Technology University of Aachen). and is planned for 31st May till 4th June 2021. Save the dates!