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Bioprinting through Levitation

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Bioprinting through Levitation

Magnetic levitation offers the possibility to place cells in a precise position in space through controlling the magnetic forces applied to magnetized cells. This new biofabrication technique, at the interface between bioprinting and bioassembly, provides new ways to create large-scale biological constructs that can be used for regenerative medicine purposes.

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SINERGIA: biofabrication for 3D in vitro models

We are excited to have been selected for funding in a Marie Curie project called SINERGIA, which aims at developing advanced models of human physiology and diseases, to be ultimately introduced in the preclinical stages of the drug discovery pipeline.

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Moroni Lab Broadcasted on Biofabrication

Biofabrication has witnessed several advances in this past months, spanning from new technologies, to promising steps forward in several tissue regeneration applications.

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Mimicking Tissue Organization at Multiple Scales with Biofabrication

Many tissues in our body display a variable degree of fiber curliness, which is crucial for their biomechanical behaviour. Methods to replicate such features in scaffolds for regenerative medicine are limited. Here, we show how by simply applying controlled buckling to electrospun fibers, we can fabricate scaffolds with different degrees of fiber waviness at multiple scales.

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Towards Kidney bioprinting

Certainly bioprinting of a full kidney remains a dream. It will be probably like that for many decades, unless a strong and well funded collaborative effort will be originated in the near future. However, current kidney bioprinting attempts are helping creating more know-how over kidney biology through the biofabrication of 3D in vitro models that can be used to study new treatments for kidney chronic conditions.

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Bioprinting through Levitation
Published on: June 5, 2020
Category: Events

Many of us have certainly vivid in their mind the image of a levitating frog by the Russian Noble prize winner Andre Geim. Exploiting the same levitation principles allows today to assemble cellular constructs in a precise manner. This is possible through magnetic or acoustic levitation principles. We have recently teamed up with scientists from 3D Bioprinting Solutions, a Russian company that is at the forefront of biofabrication technologies, to further understand the principles governing this technology. Thanks to a collaboration with the High Magnetic Field Laboratory in Nijmegen, the Netherlands, we were able to reproduce magnetic levitation principles and understand the minimum amount of magnetized agents that are possible to administer to cells to avoid any toxic effect.

To learn more, you can access EMFL newsletter (page 4):
https://emfl.eu/emflwebsite/wp-content/uploads/2020/05/emfl_newsletter_n1_20_web.pdf

and read our article published in Biofabrication:

https://iopscience.iop.org/article/10.1088/1758-5090/ab7554