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Biofabrication for the eardrum

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New Hybrid Biofabrication technology

Many tissues in our body display gradients. These are not only biological gradients, but also structural, physical, and chemical ones, resulting in smoother variations of mechanical properties and cell functional activity.

Kidney 3D in vitro models through bioprinting

At the Complex Tissue Regeneration department, we work hard to bridge the gap towards the dream of organs bioprinting. Step by step, we are now progressing towards understanding more and more in depth the requirements to bioprint different kidney cells, either derived from pluripotent stem cells or of adult species.

Bioprinting through Levitation

Magnetic levitation offers the possibility to place cells in a precise position in space through controlling the magnetic forces applied to magnetized cells. This new biofabrication technique, at the interface between bioprinting and bioassembly, provides new ways to create large-scale biological constructs that can be used for regenerative medicine purposes.

SINERGIA: biofabrication for 3D in vitro models

We are excited to have been selected for funding in a Marie Curie project called SINERGIA, which aims at developing advanced models of human physiology and diseases, to be ultimately introduced in the preclinical stages of the drug discovery pipeline.

Moroni Lab Broadcasted on Biofabrication

Biofabrication has witnessed several advances in this past months, spanning from new technologies, to promising steps forward in several tissue regeneration applications.

Published on: August 19, 2018
Category: Events

Current approaches used for eardrum repair or replacement show sub-optimal hearing outcomes. 4NanoEARDRM aims at filling an exposed gap in COM treatment by providing biomimetic, reliable and highly performant eardrum devices provided with targeted drug delivery and anti-inflammatory activity, finally enabling in situ tympanic membrane regeneration with optimal acoustics. The 4NanoEARDRM device is conceived to be “4 times” “nano”, as it will have nanofibres supportive for cell repopulation, immunomodulatory nanofibrils, drug-delivery nanoparticles, and nanoscale vibration. At the same time, it will be “for” “Nano”, namely, for enabling exploitable nanotechnologies and nanomedicine products in otologic surgery.

As part of a Euronanomed project, we will be working together with partners from Italy, Germany, and Turkey.

Sponsorship

The major aim of our lab is to develop innovative biofarication approaches for regenerative medicine as well as training next generation's talented students and postdocs.

One of the most direct ways of contributing to these causes is by donating towards a research aim or sponsoring any of our group members directly. Please contact Professor Moroni about donations towards research for fighting diseases such as osteoarthritis, cardiovascular, and neural degeneration.

We are greatful to our generous sponsors!

BioFabrication for Medicine

We create solutions for clinical problems