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Towards Kidney bioprinting

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Towards Kidney bioprinting

Certainly bioprinting of a full kidney remains a dream. It will be probably like that for many decades, unless a strong and well funded collaborative effort will be originated in the near future. However, current kidney bioprinting attempts are helping creating more know-how over kidney biology through the biofabrication of 3D in vitro models that can be used to study new treatments for kidney chronic conditions.

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World TERMIS 2021

After Seoul, Vienna, and Boston, Maastricht was selected to host the next world conference of the tissue engineering and regenerative medicine society. We expect to attract more than 2'000 delegates by 2021 in Maastricht, which is at the center of a European region fervidly active in tissue engineering, regenerative medicine, stem cells, biomaterials, in silico modeling, and biofabrication.

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Biofabrication for the eardrum

Tympanic membrane (or eardrum) is provided by nature with unique anatomic features that ultimately allow a superb physiologic performance in varying frequency ranges. Several pathologies damage this tissue, including chronic otitis media (COM), which ultimately bring to deafness.

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Biofabrication with dynamic materials

3D printing makes it possible to create complex personalized products such as prostheses and implants directly from a 3D scan. To make this type of application possible, it is important that available materials have the correct mechanical and biochemical properties. In the TA program DYNAM, which is funded from the Innovation Fund for Chemistry, researchers and companies will tackle this challenge

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New Project on 3D printing

Damaged and diseased bones in the region of head, face and jaws are common, and are conventionally treated using metallic or polymeric implants, which poorly bond to the surrounding bone. As a result, failure of such implants is common.

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Towards Kidney bioprinting
Published on: January 12, 2019
Category: Events

In this direction, we have started since 3 years to work on kidney bioprinting, with collaborations in Germany, Canada, and United Kingdom. Thanks to the leadership of Carlos Mota, asistant professor in the group, and his team we now have a better grip over the differentiation of stem cells into kidney progenitors to regenerate several of the specialized cells present in a kidney. We have devised new bioinks to maintain these cells alive during bioprinting and are currently studying differentiation processes in the bioprinted 3D in vitro models.

Carlos has also talked about the curent state of the art and challenges in a couplef interviews. To know more:

https://www.nemokennislink.nl/publicaties/nierweefsel-uit-de-3d-printer/ (in Dutch);

https://www.maastrichtuniversity.nl/news/um-institute-merln-will-develop-kidney-tissue-using-3d-bioprinting (in English);

 https://www.trouw.nl/home/stel-je-voor-een-verloren-been-groeit-vanzelf-aan~a4d095f4/ (in Dutch)